HPLC pumps
Precise Solvent Delivery for Every Application
Flow rate, mobile phase chemistry, and application scale are the defining variables of any HPLC method — and the pump is where all three meet. Sykam manufactures a range of HPLC pumps covering the full spectrum: from micro-analytical flows to semi-preparative throughput, from simple isocratic methods to complex four-solvent gradients. All pump heads are available in stainless steel or fully inert PEEK construction, and each model is engineered in Fürstenfeldbruck to deliver the flow precision and pressure stability that reliable chromatography demands.
Isocratic
S 1122 — Isocratic HPLC Pump
Reliable dual-piston delivery in a compact footprint
The S 1122 uses a short-stroke dual-piston design with just two valves — combining the simplicity of a single-piston pump with the low pulsation of a dual-piston system. Microprocessor-controlled speed regulation and continuous pressure-dependent flow correction ensure consistent, back-pressure-independent solvent delivery across the entire operating range. Purpose-built for precise isocratic workflows in routine analytics and quality control.
Specifications
- Materials
- Stainless steel or PEEK
- Flow rate — Micro
- 0,02 – 4,00 ml/min
- Flow rate — Analytical
- 0,10 – 9,95 ml/min
- Flow rate — Preparative
- 0,40 – 40,00 ml/min
- Max pressure — Micro / Analytical
- Up to 40 MPa (400 bar)
- Max pressure — Preparative
- Up to 20 MPa (200 bar) · optionally 40 MPa (400 bar)
- Compressibility
- Adjustable (0.7 – 1.0)
Applications
The S 1122's straightforward operation and robust construction make it the pump of choice for everyday isocratic HPLC — quality control, routine analysis, teaching labs, and any workflow where dependable single-flow delivery is the priority.
Isocratic / gradient
S 1125 — Isocratic / Low-Pressure Gradient Pump
Flexible delivery from micro to semi-preparative scale
The S 1125 is an exceptionally flexible and powerful solvent delivery platform, available as a straightforward isocratic pump or as the S 1125G quaternary gradient pump with optional integrated vacuum degasser. A high-performance stepper motor with intelligent motor management delivers extremely high resolution across the full dynamic flow range — from 0.001 ml/min micro-analytical up to 40 ml/min semi-preparative. The dual-piston design with electronic pressure compensation achieves minimal pulsation for reliable HPLC and GPC results.
Specifications
- Materials
- Stainless steel or PEEK
- Flow rate — Micro
- 0,001 – 4,000 ml/min
- Flow rate — Analytical
- 0,001 – 10,000 ml/min
- Flow rate — Preparative
- 0,100 – 40,000 ml/min
- Max pressure — Micro / Analytical
- Up to 40 MPa (400 bar)
- Max pressure — Preparative
- Up to 20 MPa (200 bar) · optionally 40 MPa (400 bar)
- Flow precision
- ± 0,1 % RSD
- Mixer volume (S 1125G)
- Adjustable: 10 – 500 µl
Applications
The S 1125's versatility makes it suitable for virtually all areas of analytical chemistry — from pharmaceutical QC and method development to ion chromatography and GPC. A single instrument covers micro, analytical, and semi-preparative scale.
Platform
S 1130 — Isocratic / Low- and High-Pressure Gradient Pump
One pump platform, three configurations
The S 1130 is Sykam's most versatile pump platform — configurable as an isocratic pump, a quaternary low-pressure gradient system (S 1130G), or a binary high-pressure gradient pump (S 1132), with the option to combine configurations into multi-flow systems. A high-performance stepper motor delivers outstanding resolution at low flow rates, and the sealed, permanently lubricated camshaft keeps maintenance requirements minimal. Optional integrated vacuum degasser and active piston back-flushing available.
Specifications
- Materials
- Stainless steel or PEEK
- Flow rate — Micro
- 0,001 – 2,000 ml/min
- Flow rate — Analytical
- 0,001 – 10,000 ml/min
- Max pressure
- Up to 40 MPa (400 bar)
- Compressibility
- User-adjustable for different solvents
- Mixing accuracy (S 1130G)
- < 0,25 %
- Mixer volume (S 1130G)
- Adjustable: 10 – 500 µl
Applications
The S 1130's versatility makes it suitable for virtually all areas of analytical chemistry operating within the micro-to-analytical flow range — pharmaceutical analysis, ion chromatography, GPC, and research applications requiring gradient elution.
Syringe pump
S 1610 — Syringe Pump
Completely pulse-free delivery for post-column derivatisation and complex media
The S 1610 syringe pump is designed for continuous and discontinuous delivery of complex media up to approximately 25 bar. Two interchangeable inert ILS syringes cover a wide range of flow capacities, while a force-controlled motor valve ensures reliable operation even with high biomass content. The completely pulse-free delivery — with a resolution of 1:4000 — makes the S 1610 especially well suited to post-column derivatisation, where flow stability is critical to detection quality.
Specifications
- Materials
- Stainless steel, PEEK, or quartz glass
- Max pressure
- Approx. 25 bar (continuous and discontinuous)
- Resolution
- 1:4000
- 1 ml syringe
- Up to 8 ml/min
- 2.5 ml syringe
- Up to 20 ml/min
- 5 ml syringe
- Up to 40 ml/min
- 10 ml syringe
- Up to 80 ml/min
Applications
The S 1610 is the pump of choice for samples with high biomass content and for workflows requiring post-column derivatisation — including amino acid analysis, carbohydrate determination, and polyamine analysis.
Quaternary gradient
S 2100 — Quaternary Gradient Pump
Compact, feature-rich gradient pump with on-board diagnostics and graphical display
The S 2100 is a compact dual-piston high-pressure pump with an integrated quaternary low-pressure gradient mixer, covering micro, analytical, and preparative HPLC from a single platform. Intelligent modules provide real-time graphical display of gradient and pressure profiles, with on-board system monitoring and diagnostics. Freely programmable relay outputs allow seamless integration into existing instrument pools. Optional integrated vacuum degasser available.
Specifications
- Materials
- Stainless steel or PEEK
- Flow rate — Micro
- 0,01 – 2,00 ml/min
- Flow rate — Analytical
- 0,05 – 10,00 ml/min
- Flow rate — Preparative
- 0,2 – 40,0 ml/min
- Max pressure — Stainless steel
- Up to 40 MPa (400 bar)
- Max pressure — PEEK
- Up to 30 MPa (300 bar)
- Gradient accuracy
- 0.1% steps, 4 channels
Applications
The S 2100's flexibility and diagnostic capability make it suitable for virtually all areas of analytical chromatography — pharmaceutical development, environmental analysis, food testing, and research. Its compact footprint and relay control outputs make it straightforward to integrate into existing multi-instrument setups.
Not sure which pump configuration suits your method? Contact us — we're happy to help you select the right system for your flow range, mobile phase, and application.