Complete systems

Integrated Chromatography Platforms, Ready for Your Application

When pumps, injectors, ovens, detectors, and software are matched to the same separation chemistry, you spend less time tuning hardware and more time producing reliable data. Sykam complete systems combine proven modules into pre-configured lines for amino acid analysis, routine and research HPLC, ion chromatography, and radiochemical purity testing. Each platform is assembled, tested, and documented in Fürstenfeldbruck so you can move from installation to validated workflows without guesswork.

Sykam modular chromatography systems and instrumentation

Amino acid analysis

S 433 — Automatic Amino Acid Analyser

Classical ion-exchange separation combined with modern HPLC technology

The innovative, automatic amino acid analyser S 433 combines the advantages of classical ion-exchange separation with modern HPLC technology. The complete package of well-designed modules, the wide variety of pre-packed and tested separation columns, combined with optimised ready-to-use buffer solutions and reagents, is the right answer for every routine or research problem in amino acid determination.

Applications

The S 433 amino acid analyser is designed for fully automated routine analysis. With optionally available buffers, the separation of all physiologically important amino acids is guaranteed.

Sykam S 433 automatic amino acid analyser

HPLC

S 600 Series — Analytical HPLC Systems

Pre-configured, freely expandable systems for every analytical task

HPLC systems are required for a wide variety of applications, which makes it challenging to find the right combination of individual components. Our pre-configured S 600 Series HPLC systems can be freely assembled and easily expanded at a later stage — specialised for a single application or designed for multiple different analyses. It is straightforward to combine different detection methods, provided the physical properties of the analytes allow it. We are happy to assist you in configuring the right system for your needs.

Configuration options

Solvent delivery
Isocratic · Low-pressure gradient · High-pressure gradient
Flow range
Micro-analytical · Analytical · Preparative
Detection
UV/Vis · Refractive index · Conductivity · Radioactivity · Light scattering

Applications

Thanks to their modular design, our HPLC systems are suitable for all fields.

Sykam S 5300 autosampler as part of an analytical HPLC system

Biotech

Biotech — Inert Fluid Paths for Sensitive Workflows

PEEK, PTFE, and biocompatible modules for biomolecule-friendly chromatography

When metal contact must be avoided, Sykam biotech systems combine inert pumps, autosamplers, valves, and flow paths with the same precision as our analytical lines. Configure PEEK or PTFE wetted surfaces, high-salt buffers, and dedicated biotech autosamplers for protein, peptide, and ion workflows.

Sykam biotech-compatible chromatography modules

Ion chromatography

S 150 / S 151 — Pre-Configured Ion Chromatographs

Reliable determination of anions, cations, and organic acids

With our pre-configured ion chromatograph, a wide variety of anions, cations, and organic acids can be reliably determined in the shortest time. By coupling different detectors, the system's sensitivity can be adapted to a wide range of sample concentrations, ensuring an optimal result at all times.

System specifications

Material
Stainless steel or PEEK
Flow range
Micro 0.001–4.000 ml/min · Analytical 0.001–10.000 ml/min · Preparative 0.100–40.000 ml/min
Pressure
Micro/Analytical up to 40 MPa (400 bar) · Preparative up to 20 MPa (200 bar) or 40 MPa (400 bar)
Detectors
Conductivity · UV/Vis · Refractive index
Injection
Manual · Autosampler 60 vials · Autosampler 120 vials · Microtiter plate injection

Applications

The ion chromatograph is suitable for all areas of water analysis.

Sykam S 150 conductivity detection for ion chromatography

Radiopharmaceutical QC

Radio-HPLC

Pre-configured for the most common decay-measurement challenges

The pre-configured Radio-HPLC is designed as standard to cover the most common challenges in decay measurements. We offer a system with a highly sensitive NaI(Tl) scintillation detector that, together with the integrated photomultiplier and 4π well-type geometry, delivers excellent sensitivity.

Both gamma and positron radiation can be detected. All peak intensities are automatically half-life corrected in the data software to maximise reproducibility and accuracy of measurements.

Integrated valves (partly optional) and the sample loops used ensure high flexibility across the activity levels you employ. For effective shielding and staff protection, all fluid-contacting parts are shielded, largely minimising radiation exposure for the operator.

Radio-HPLC specifications

Material
Stainless steel or PEEK
Detector
NaI(Tl) scintillation detector with photomultiplier
Maximum sensitivity
511 keV

Applications

The Radio-HPLC is designed for routine diagnostics and analytics in clinical environments.

Sykam S 3700 radioactivity detector for Radio-HPLC workflows

Need a system layout outside the standard configurations? Contact us — we will match modules, chemistry, and software to your methods and regulatory context.